TORONTO (AP) -- Jose Bautista homered and drove in two runs, R.A. Dickey won for the first time in three starts and the Toronto Blue Jays beat the Boston Red Sox 6-4 on Wednesday night.
Bautista hit an RBI double in the first inning and added a leadoff homer in the seventh, his first since July 2.
David Ortiz hit a three-run homer for the Red Sox, his fourth in three games, but Boston lost its second straight after winning the previous five.
Dickey (8-10) allowed four runs and nine hits in six innings, walked one and struck out five.
Rookie Aaron Sanchez, selected from Triple-A Buffalo on Tuesday, made his debut with two perfect innings and Casey Janssen finished for his 15th save.
The Red Sox went up 3-0 before Dickey could record an out. After Shane Victorino and Dustin Pedroia singled to start the game, Ortiz followed with a towering drive off the facing of the fourth deck. The homer was his 455th, tying him with Adam Dunn of the Chicago White Sox for 35th on the career list.
Ortiz’s drive was his 37th at Rogers Centre, breaking a tie with Alex Rodriguez for the most by a visiting player.
Ortiz, who went deep in homered in three straight games for the first time since June 17-20, 2012.
The three RBI gave Ortiz 1,501 for his career, making him the 53rd player in major league history with 1,500 or more.
Staked to an early lead, Red Sox right-hander Clay Buchholz couldn’t make it stand up for long as the Jays tied the score in the bottom of the inning.
Boston reclaimed the lead with consecutive doubles by Nava and Xander Bogaerts in the fifth, but Toronto answered with two runs off Buchholz in the sixth. Thole walked and scored on Ryan Goins’ first career triple. Two batters later, Goins scored on a throwing error by shortstop Bogaerts.