After all the pomp and circumstance is cleaned up after inauguration weekend, many are wondering: What next?

After President-elect Donald Trump is sworn in as the United States' 45th president on Friday, his supporters, detractors, Congress, the media and political observers await to see what the business mogul turned Commander-in-Chief will do in his first 100 days in the Oval Office.

Trump's zero government experience worries some, others see him as a fresh approach to dealing with pressing issues, such as health care, immigration and job growth.

No matter the resume, a first-term president is on a learning curve of how the federal government works, according to political science professor Samantha Pettey at the Massachusetts College of Liberal Arts in North Adams, Mass.

"It's important to recognize the institutional rules and respect those rules," Pettey said. "Congress is a very slow-moving branch and it's designed that way. Will that frustrate Trump?"

Whether on his own authority, or approval from Congress, the incoming president won't necessarily find his decisions easily implemented.

"Trump will find, unlike the business world, he can't snap his fingers and get things done," said Justin Crowe, associate professor of political science at Williams College in Williamstown, Mass.

What happens those first '100 days'?

"One hundred days is almost not fair for a new presidency in this day in age. It's hard to imagine the first 100 days just like FDR," said Crowe.

What he is referring to is the time period first associated with Franklin Delano Roosevelt during his inaugural term 84 years ago. The 100 days gauges the successes and accomplishments of a president during a time that political pundits consider the chief executive's power and influence is at its greatest. Roosevelt coined the term referring to the 100-day session of the 73rd U.S. Congress between March 9 and June 17, rather than the first 100 days of his administration.

Nevertheless, on Day 1 of the new Congress in 1933, the legislative body passed Roosevelt's Emergency Banking Act, the first in a series of steps FDR spearheaded to pull the U.S. out of the depths of the Great Depression.

How do the seats get filled?

Trump will immediately lock horns with some members of the U.S. Senate, charged with approving his cabinet appointees and more than a thousand other agency heads and senior posts, according to a recent CNN online report. While Senate hearings vetting the nominations have been under way for two weeks, Senate votes can only happen after Trump takes office on Friday. Once the nomination is considered by the Senate, unlimited debate is allowed until two-thirds of the Senate vote to end the debate. The Senate then conducts a majority vote on whether to confirm, reject or take no action on the nomination.

What about my health insurance?

Trump and Congress' potential repeal of the Affordable Care Act has millions of American's enrolled in the program worried.

Crowe doubts Trump and Congress can ill-afford a straight-up substitution of the health insurance program.

"There is simply no way the Republicans are going to cover all those Americans under a repeal of 'Obamacare,'" he said. Keep in mind that many steps remain before any changes will take affect. If you're one of the estimated 20 million Americans who gained coverage through the health law, you are extremely unlikely to lose coverage this year, according to a report by The New York Times.

It's a complicated issue, but the short answer is we'll have to wait and see.

How the U.S. House and Senate handle healthcare is on par with Trump dealing with the issue, according to Pettey.

"I would argue we have a representative government and [Americans] should pay attention to what Congress does," she said.

But the president can flex some muscle, right?

Pettey and Crowe point out Trump's more immediate impact could come via executive orders, such as securing the nation's borders and setting the tone on foreign policy. Trump has vowed to give border patrols more vetting powers over those coming into the country, especially from Mexico.

The president-elect has also raised eyebrows in the Middle East by considering moving the U.S. Embassy in Israel from Tel Aviv to Jerusalem, according to a USA Today report.

Israelis have been pushing countries to relocate their diplomatic missions to Jerusalem on the West Bank, a city both Israel and the Palestinians claim as their capital. Palestinian leaders and other Arab nations have balked at the potential move, believing it will trigger more violence in the tension-filled region.

Trump must weigh the risks of this and any executive order he issues, according to Pettey.

"Technically, the president can make such orders because he oversees the bureaucracy, but that doesn't mean they are necessarily appropriate things to do," she said.